Researchers convey sounded a alarm afterwards the results of a 10-year study suggested 2 strains of flu could mix too shape a unsafe novel strain of flu spread past times dogs.
Associate Professor Daesub Song, of Korea University inward Seoul, has called for closer monitoring of dogs too other companion animals every bit they could endure a source of novel human flu strains.
“Until now, dogs were considered neglected hosts inward the plain of flu research,” he said.
“However, afterwards the commencement study of interspecies transmission, surveillance of flu viruses from companion animals should endure farther strengthened.”
In the 2000s, several cases of viruses crossing the host barrier were recorded.
Most notably, H3N2 aeroplane flu crossed over to dogs too developed into Canine Influenza virus (CIV).
Song’s query has found that this H3N2 CIV could combine with H1N1/2009 too shape a novel flu virus, called CIVmv.
The emergence of novel species of flu such every bit this is concerning.
Those infected volition convey non come upwards into contact with a virus similar this before, important they would non convey immunity to the disease.
If the virus could endure carried too spread to humans from companion animals, it could convey the potential to spread throughout the population extremely quickly.
H1N1/2009 is known for causing the 2009-2010 global “swine flu” pandemic. When this strain of flu combines with CIV inward dogs, unopen to of the viruses recombine to shape CIVmv.
Although CIVmv is really similar to CIV, researchers convey calculated at that topographic point is a much higher opportunity of the illness spreading to humans due to its high infection rates inward ferrets.
Viruses bind to host cells too drive infection via sialic acid (SA) receptors, which differ betwixt species. Ferrets convey really similar SA receptors to humans. Because of this, ferrets are considered the close reliable experimental model for predicting too evaluating the opportunity of novel human flu viruses.
During their studies of the novel CIVmv strain, Song noted that infected dogs too ferrets displayed typical symptoms of respiratory disease, including congestion, breathing difficulties, coughing, runny eyes, sneezing, lethargy, too appetite loss.
As good every bit these symptoms, he reported that the novel strain spread betwixt ferrets to a greater extent than apace than other flu viruses too replicated quickly.
Researchers are trying to develop a vaccine for the virus. However, due to the high score of mutations, vaccines are really hard to develop.
Despite existence named Canine Influenza Virus, it is non but dogs that tin hand notice endure infected past times CIV.
During the ten-year study, researchers found that cats were besides susceptible to the virus. Dr Song investigated an outbreak of CIV inward an animate existence shelter, during which 100% of the cats were infected too 40% died.
The evolution of susceptibility inward cats is worrying every bit it shows that CIV tin hand notice spread with unlike animate existence species.
Researchers convey raised concerns every bit at that topographic point is a potential for the virus to locomote endemic inward companion animals.
As both dogs too cats are inward frequent contact with humans, much to a greater extent than oftentimes than pigs or chickens, the potential opportunity for a novel strain to develop too infect humans is fifty-fifty higher.
Since existence commencement identified inward South Korea, CIV has spread to China, Thailand too the United States.
A illustration of CIVmv infection was identified inward a Canis familiaris inward 2012 next an epidemic of H1N1. Song used this strain inward ferrets to create upwards one’s heed whether it had the potential to spread from canines to humans. From there, a novel human flu strain could emerge.
“Pre-existing CIV may recombine or reassort with human flu viruses too hand ascent to novel viruses that could inward plough atomic number 82 to unique pandemics,” he said.
Livestock illness query inward spotlight
In recent days to a greater extent than than 50 researchers, academics, regime representatives too policy makers convey met inward the Philippines to speak over strategies to tackle livestock diseases that have the potential to infect people.
More than 60% of electrical flow infections inward humans originate from animals, too a major challenge to sustainable increment inward the fast-growing livestock production sector of the nutrient manufacture is the many diseases – viral, bacterial too parasitic – which tin hand notice terms productivity.
After the gathering led past times Britain’s Lancaster University too the University of the Philippines, Dr Munir Muhammad, from Lancaster’s Faculty of Health too Medicine, said the links established would supply foundations to mutually tackle infectious diseases inward livestock too humans inward the close future.
Because of the global nature of many of these diseases, it is of import for agencies to operate together to uncovering ways to cut back the risk.
During workshops, researchers discussed the major challenges too query advances inward the command of livestock diseases.
In other sessions, delegates discussed the component of academia inward driving livestock illness research, the importance of developing improve illness measures, livestock illness impacts on humans, too the contribution past times the farming sector inward developing countries.